Endocrine Abstracts

Introduction: The cystic nodule is an unusual presentation of papillary thyroid carcinoma (PTC), seen in less than 10% of cases. Ultrasound discovery of a thyroid cyst represents less than 5% risk of malignancy. We report the case of a patient followed for papillary thyroid carcinoma in its cystic form.Observation: A 42-year-old patient with no specific history. The patient underwent a right isthmolobectomy for a thyroid nodule. Anatomopathological exami...

Introduction: Pheochromocytomas are rare neuroendocrine tumors producing catecholamines, they are usually unilateral. However, they can be located bilaterally. They still pose several problems in their diagnosis if they are associated with an adrenal cyst, which is the case in our patient.Case Report: A 34-years-old male patient, his medical and family histories were non specific, admitted to the emergency room for lumbar pain, with no other associated s...

Introduction: Neurofibromatosis type 1(NF1) is an autosomal dominant genodermatosis that affect multiple organs. It represents one of the most frequent genetic diseases. The diagnosis is primarily clinical and is based on the NIH criteria (National Institutes of Health) established in 1988, and revised in 2021. We report a case of male patient with NF1 revealed by a pheochromocytoma.Case Report: A 26-years-old man patient with no previous medical history...

Introduction: Partial 21-hydroxylase deficiency is a genetic autosomal recessive disorder responsible for accumulation of the precursor upstream of the enzyme block, 17-hydroxyprogesterone (17OHP), and excessive androgen production.Observation: A 29-year-old woman consulted for hirsutism with a Ferriman–Gallwey score of 25. There were no signs of Cushing syndrome and no abnormalities of sexual development. The Laboratory results revealed testosteron...

Introduction: Pheochromocytoma is a rare neuroendocrine tumor. It is usually diagnosed in subjects between 40 and 50 years of age. The occurrence of pheochromocytoma in the elderly is much rarer and has its own particularities. We report the case of a 70-year-old female patient with invasive pheochromocytoma.Case presentation: A 70-year-old female patient with a history type 2 diabetes for 18 years on oral antidiabetics and insulin. The history of his di...

Introduction: Hypercalcemia is often observed in patients with cancer, secondary to the production s of parathyroid hormone (PTH)-related peptides. However, the association of primary hyperparathyroidism (pHPT) and colon cancer is rarely reported.Case: We present the case of a 76 years old female patient, who was operated one year ago of for a low-grade colorectal adenocarcinoma. As part of her routine workup of her disease she underwent a phosphocalcic ...

Introduction: Primary hyperparathyroidism revealed by multiple brown tumors is rare. We report the case of a patient with primary hyperparathyroidism on parathyroid adenoma discovered in front of multiple brown tumors.Case Presentation: A 72-year-old female patient, who presented for 6 months a functional impotence of both lower limbs with paraparesis, associated with bone pain from where the realization of a phospho-calcium assessment returning in favor...

Introduction: Primary hyperparathyroidism is a frequent pathology, its association with papillary thyroid carcinoma is rare.Case Report: A 53 year old patient was admitted for management of primary hyperparathyroidism. The biological work-up showed a blood calcium level of 120 mg/l, parathyroid hormone (PTH) 4 times the normal range and hypophosphatemia. Cervical ultrasound showed a right parathyroid nodule with thyroid nodules classified Tirads 4, MIBI ...

Introduction: Primary hyperparathyroidism is the most common endocrinopathy after diabetes and thyroid diseases. Most often, the diagnosis is made at the asymptomatic stage due to the frequent phosphocalcic assessment objectifying hypercalcemia. Much more rarely, primary hyperparathyroidism is diagnosed at the stage of digestive, renal or bone complications. We report the case of a young patient with a femoral fracture that revealed primary hyperparathyroidism.<p class="ab...

Introduction: Mucormycosis is a rare, devastating, fungal infection, which disproportionately affects non-controlled diabetic patients, notably during ketoacidosis. It is a potentially lethal disease. The diagnosis and treatment of mucormycosis remain a challenge because of the nonspecific clinical presentation. We discuss the clinical features and management modalities of this case.Case: We report the observation of a 41 years old male patient, who had ...